产品名称

Trehalose 6,6′-dimycolate from Mycobacterium bovis

一般描述

Cord factor is a glycolipid released from Mycobacterium that becomes toxic and antigenic when it interacts with cell surface lipids.

别 称

6,6’-Di-O-mycoloyl-α,α-trehalose from Mycobacterium bovis, Cord factor from Mycobacterium bovis

含 量

≥97%(6,6′-mycolate esters basis)

CAS NO.

61512-20-7

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至灰白色粉末

旋光度

[α]25/D 32 to 35 °, c = 1% (w/v) in chloroform/methanol/water (10:9:1)

l  生物学信息

生物活性/药理作用

Cord factor is a glycolipid released from Mycobacterium that becomes toxic and antigenic when it interacts with cell surface lipids. It activates macrophages to release inflammatory cytokines and induces thymic atrophy and granuloma formation in lung and other organs. It is responsible for the necrosis and cavitation observed in secondary tuberculosis.

l  存储

存储温度

−20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov