产品名称

Filipin III from Streptomyces filipinensis(非律平 III 来源于菲律宾链霉菌)

一般描述

Filipin is a polyene macrolide antibiotic and antifungal.

别 称

Filimarisin;Filipine

纯 度

≥85%(HPLC)

CAS NO.

480-49-9

分子式

C³⁵H⁵⁸O¹¹

分子量

654.83

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至黄色粉末

l  生物学信息

生物活性/药理作用

Filipin is a polyene macrolide antibiotic and antifungal. The antifungal mechanism of action may be due to altering membrane permeability and associated functions by binding to membrane sterols. Filipin inhibits prion protein (PrP) endocytosis and causes the release of PrP from the plasma membrane.

应 用

Filipin has been used in a double staining procedure as a probe for the detection of lipoproteins in polyacrylamide gel and immobilized on nitrocellulose membranes. It is also widely used to localize and quantitate unesterified cholesterol by virtue of a specific fluorescent complex.

l  存储

存储温度

−20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov