Cytochalasin B from Drechslera dematioidea
商品编号：
S1305
备注：
国外库存，货期2-4周，具体详情请联系销售人员。
详细介绍
l 基本信息 |
产品名称 | Cytochalasin B from Drechslera dematioidea(细胞松弛素B来源于Drechslera dematioidea) |
一般描述 | Cytochalasin B is a cell-permeable fungal toxin / mycotoxin that binds to the ‘barbed’ end of actin / actin filaments. |
别 称 | Phomin |
纯 度 | ≥98%(HPLC) | CAS NO. | 14930-96-2 |
分子式 | C29H37NO5 | 分子量 | 479.61 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 白色粉末 |
溶解性(25°C) | DMSO | ≥5mg/mL |
l 生物学信息 |
生物活性/药理作用 | Cytochalasin B is a cell-permeable fungal toxin / mycotoxin that binds to the ′barbed′ end of actin / actin filaments. This binding leads to: •
Disruption of actin filaments and of interaction of actin filaments in solution •
Inhibition of actin polymerization •
Inhibition of subunit association and dissociation Cytochalasin B is widely used in studies of glucose transporters (GLUT). Cytochalasin B is also used as an integral part of various in vitro micronucleus assay protocols. One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts. |
l 存储 |
存储温度 | −20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
