产品名称

Phalloidin from Amanita phalloides(鬼笔环肽来源于鬼笔鹅膏)

一般描述

Phalloidin interacts with polymeric actin, and not oligomeric or monomeric forms. This interaction leads to highly stabilized actin filaments, which resist depolymerization and disassembly.

纯 度

≥90%(HPLC)

CAS NO.

17466-45-4

分子式

C³⁵H⁴⁸N⁸O¹¹S

分子量

788.87

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色粉末

l  生物学信息

生物活性/药理作用

Phalloidin interacts with polymeric actin, and not oligomeric or monomeric forms. This interaction leads to highly stabilized actin filaments, which resist depolymerization and disassembly. In rats, this toxin causes death due to liver hemorrhage and cells show abnormal actin clustering. The affinity of phalloidin to actin is not significantly altered after derivatizing fluorescently labelled phalloidin compounds. These compounds can be used to study actin structure and organization within eukaryotic cells.

应 用

Phalloidin has been used:

• As a supplement in PEM buffer and dimethyl sulfoxide (DMSO).

• As a drug.

• In immunohistochemistry to stain F-actin.

l  存储

存储温度

−20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov