产品名称

(±)-Gossypol from cotton seeds((±)-棉酚来源于棉花种子)

一般描述

Gossypol is a male antifertility agent and PAF antagonist/inhibitor. Gossypol is a poisonous pigment found in cottonseed and its name is derived from the botanical name of the cotton plant, Gossypium.

别称

(±)-2,2′-bis(8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene)

纯 度

≥95%(HPLC)

CAS NO.

303-45-7

分子式

C³⁰H³⁰O⁸

分子量

518.55

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

黄色与棕色到绿色粉末

l  生物学信息

生物活性/药理作用

Gossypol is a male antifertility agent and PAF antagonist/inhibitor. Gossypol is a poisonous pigment found in cottonseed and its name is derived from the botanical name of the cotton plant, Gossypium. Gossypium is extracted from selected hybrid species between two Gossypium species, Gossypium hirsutum and Gossypium barbadens. As a PAF antagonist/inhibitor, Gossypium markedly inhibited the contractile responses of guinea pig lung parenchyma strips stimulated with leukotriene B4, seukotriene D4, and PAF-acether.

应 用

(±)-Gossypol from cotton seeds has been used:

•  as a standard to quantify the gossypol content in the extracts of leaves and  flower buds

•  to study its antifertility effects on spermatogenesis in NMRI mice

•  to analyse its impact on human spermatozoa

•  to incorporate into the artificial diet for larval rearing

l  存储

存储温度

2-8°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov