产品名称

Gramicidin A from Bacillus brevis(短杆菌素A 来源于短芽孢杆菌)

一般描述

Gramicidin A is a linear pentadecapeptide antibiotic produced by Bacillus brevis. The transmembrane protein contains a left-handed helix with alternating L and D residues.

别 称

Valyl gramicidin A

纯 度

≥90%(HPLC)

CAS NO.

11029-61-1

分子式

C⁹⁹H¹⁴⁰N²⁰O¹⁷

分子量

1882.332

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至类白色固体

l  生物学信息

生物活性/药理作用

Gramicidin A is a polypeptide antibiotic that forms single ion monovalent cation channels in biological membranes. Gramicidin A increases the permeability of bacterial cell membranes, which allows inorganic monovalent cations to travel through unrestricted. This destroys the ion gradient between the cytoplasm and the extracellular environment. Gramicidin A acts as neutral carrier and helps in the establishment of ion flux across the lipid b.

应 用

Gramicidin A is used for studies on bacterial cell wall permeabilization and monovalent cation channel formation.

l  存储

存储温度

2-8°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov