产品名称

Streptonigrin from Streptomyces flocculus(链黑霉素 来源于柔毛链霉菌)

一般描述

Streptonigrin (SN) is an aminoquinone antitumour antibiotic.

别 称

Bruneomycin, Nigrin

纯 度

≥98%(HPLC)

CAS NO.

3930-19-6

分子式

C²⁵H²²N⁴O⁸

分子量

506.46

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

非常深红色和非常深红棕色粉末

l  生物学信息

生物活性/药理作用

Streptonigrin (SN) is an aminoquinone antitumour antibiotic. Its antineoplastic activity requires reductive activation by Xanthine-converting enzymes. It induces apoptosis by a mechanism involving NF-κB. DNA cleavage reaction and chromosome damage by SN are influenced by the nature of the metal ion present and dependent on the production of free radicals. Its antibiotic activity is iron-activated.

l  存储

存储温度

2-8°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov