产品名称

β-Amanitin from Amanita phalloides

一般描述

β-Amanitin belongs to the family of amatoxins.Amanitins are made of bicyclic octapeptides.

别 称

BETA-AMANITIN; Beta-Amanitin From Amanita Phalloides

纯 度

~90%(HPLC)

CAS NO.

21150-22-1

分子式

C³⁹H⁵³N⁹O¹⁵S

分子量

919.95

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至黄色至棕色粉末

l  生物学信息

生物活性/药理作用

Toxic constituent of the mushroom, Amanita phalloides, inhibits eukaryotic RNA polymerase II and III, but not RNA polymerase I or bacterial RNA polymerase. Inhibits mammalian protein synthesis.

应 用

β-Amanitin from Amanita phalloides has been used:

•  as a calibration standard for the quantification of β-Amanitin using liquid chromatography-high resolution-mass spectrometry/mass spectrometry (LC-HR-MS/MS) method.

•  to determine its concentration in urine samples by capillary zone electrophoresis (CZE).

•  in the analysis of β-amanitin in toxic mushrooms by liquid chromatography coupled to time-of-flight mass spectrometry.

l  存储

存储温度

−20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov