产品名称

左氧氟沙星(Levofloxacin)

一般描述

Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the   bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA tranion, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.

别 称

(−)-Ofloxacin;Levaquin; Quixin; Iquix; Levofloxacine;

纯 度

≥98%(HPLC)

CAS NO.

100986-85-4

分子式

C¹⁸H²⁰FN³O⁴

分子量

361.37

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至淡黄色固体

溶解度(25℃)

DMSO

≥20mg/mL

乙醇

~10mg/mL

水

~10mg/mL

l  生物学信息

生物活性/药理作用

Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the   bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA tranion,and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.

l  包装与存储

包 装

1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.   https://www.ncbi.nlm.nih.gov