产品名称

盐酸普鲁卡因(Procaine HCl)

一般描述

Procaine HCl is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties.

别 称

4-Aminobenzoic acid 2-diethylaminoethyl ester hydrochloride; Novocaine hydrochloride;

纯 度

≥99%(HPLC)

CAS NO.

51-05-8

分子式

H²NC⁶H⁴CO²CH²CH²N(C²H⁵)²·HCl

分子量

272.77

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25℃)

DMSO

≥50mg/mL

乙醇

Insoluble

水

≥50mg/mL

l  生物学信息

生物活性/药理作用

Procaine Hydrochloride is the hydrochloride salt form of procaine, a benzoic acid derivative with local anesthetic and antiarrhythmic properties. Procaine binds to and inhibits voltage-gated  sodium channels, thereby inhibiting the ionic flux required for the initiation and conduction of impulses. In addition, this agent increases electrical excitation threshold, reduces rate of rise of action potential and slows nerve impulse propagation thereby causing loss of sensation.

l  包装与存储

包 装

250mg; 1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.   https://www.ncbi.nlm.nih.gov