产品名称

环磷酰胺一水合物(Cyclophosphamide monohydrate)

一般描述

Cyclophosphamide(环磷酰胺) is the precursor of an alkylating nitrogen mustard antineoplastic and  immunosuppressive agent that must be activated in the liver to form the  active aldophosphamide.

别 称

2-[Bis(2-chloroethyl)amino]tetrahydro-2H-1,3,2-oxazaphosphorine 2-oxide;hydrate; Cyclophosphamide hydrate;Endoxan monohydrate;Cytoxan

纯 度

≥99%(HPLC)

CAS NO.

6055-19-2

分子式

C⁷H¹⁵Cl²N²O²P · H²O

分子量

279.098

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色固体

溶解性(25℃)

DMSO

≥50mg/mL

乙醇

≥10mg/mL

水

≥10mg/mL

l  生物学信息

生物活性/药理作用

Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer. Cyclophosphamide therapy is associated with minor transient serum enzyme elevations and has been ed to rare cases of acute liver injury. In addition, when given in high doses as a part of a myeloablative therapy, cyclophosphamide can cause acute sinusoidal  obstruction syndrome.

l  包装与存储

包 装

250mg;  1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.  https://www.ncbi.nlm.nih.gov