产品名称

尼氟酸(Niflumic acid)

一般描述

Niflumic acid(尼氟酸) is able to inhibit both phospholipase A2 as well as COX-2, thereby acting as an antiinflamatory and pain reduction agent.

别 称

2-[3-(trifluoromethyl)anilino]pyridine-3-carboxylic acid; 尼氟灭酸;氮氟灭酸;2-(3-三氟甲基苯胺基)烟酸;Nifluril;  Landruma; Forenol;

纯 度

≥99%(HPLC)

CAS NO.

4394-00-7

分子式

C¹³H⁹F³N²O²

分子量

282.222

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

浅黄色固体

溶解性(25℃)

DMSO

≥40mg/mL

乙醇

Insoluble

水

Insoluble

l  生物学信息

生物活性/药理作用

Niflumic acid, a nonsteroidal anti-inflammatory fenamate, is a Ca₂₊-activated Cl- channel blocker.

Niflumic Acid is only found in individuals that have used or taken this drug. It is an analgesic and anti-inflammatory agent used in the treatment of rheumatoid arthritis. Niflumic acid is able to inhibit both phospholipase A2 as well as COX-2, thereby acting as an antiinflamatory and pain reduction agent.

l  包装与存储

包 装

250mg; 1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.   https://www.ncbi.nlm.nih.gov