产品名称

异烟肼(Isoniazid)

一般描述

Isoniazid(异烟肼) is a synthetic derivative of nicotinic acid with anti-mycobacterial  properties.

别 称

pyridine-4-carbohydrazide

纯 度

≥99%(HPLC)

CAS NO.

54-85-3

分子式

C⁶H⁷N³O

分子量

137.142

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25℃)

DMSO

≥20mg/mL

乙醇

≥20mg/mL

水

≥20mg/mL

l  生物学信息

生物活性/药理作用

Isoniazid is a synthetic derivative of nicotinic acid with anti-mycobacterial properties. Although its mechanism of action is still unclear, isoniazid appears to block the synthesis of mycolic acids, major components of the mycobacterial cell wall. This agent is only active against actively growing mycobacteria because, as a pro-drug, it requires activation in susceptible mycobacterial species. Isoniazid also interferes with mycobacterial metabolism of vitamin B6. Resistance occurs due  to decreased bacterial wall penetration.

l  包装与存储

包 装

1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.   https://www.ncbi.nlm.nih.gov