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Ursodeoxycholic acid

商品编号: TL0198
图示 货号 库存 价格(¥) 数量

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质量文档

详细介绍

l  基本信息

产品名称

熊去氧胆酸(Ursodeoxycholic acid)

一般描述

Ursodiol(熊去氧胆酸), a synthetically-derived form of ursodiol, dissolves or prevents cholesterol gallstones by blocking hepatic cholesterol production and decreasing bile cholesterol.

别 称

(4R)-4-[(3R,5S,7S,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoic acid; Ursodiol

纯 度

≥98% (HPLC)

CAS NO.

128-13-2

分子式

C24H40O4

分子量

392.58

适用范围

生物试剂,适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25)

DMSO

≥50mg/mL

乙醇

≥50mg/mL

Insoluble

l  生物学信息

生物活性/药理作用

Ursodiol (also known as ursodeoxycholic acid) is one of the secondary bile acids, which are metabolic byproducts of intestinal bacteria. Primary bile acids are produced by the liver and stored in the gall bladder. When secreted into the colon, primary bile acids can be metabolized into secondary bile acids by intestinal bacteria. Primary and secondary bile acids help the body digest fats. Ursodeoxycholic acid helps regulate cholesterol by reducing the rate at which the intestine absorbs cholesterol molecules while breaking up micelles containing cholesterol. Because of this property, ursodeoxycholic acid is used to treat gall stones  non-surgically.

Ursodiol is a synthetically-derived form of ursodiol, a bile acid produced by the liver and secreted and stored in the gallbladder. Also produced by the Chinese black bear liver, ursodiol has been used in the treatment of liver disease for centuries. This agent dissolves or prevents cholesterol gallstones by blocking hepatic cholesterol production  and decreasing bile cholesterol. Ursodiol also reduces the absorption of  cholesterol from the intestinal tract.

l  包装与存储

包 装

250mg; 1g

存储温度

0-5

l  注意事项及免责声明

本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.   https://www.ncbi.nlm.nih.gov