产品名称

布洛芬(Ibuprofen)

一般描述

Ibuprofen(布洛芬), a propionic acid  derivate, is an anti-inflammatory inhibitor targeting COX-1 and COX-2, with anti-inflammatory, analgesic, and antipyretic effects.

别 称

2-[4-(2-methylpropyl)phenyl]propanoic acid;  Motrin; Brufen; Advil

纯 度

≥99%(HPLC)

CAS NO.

15687-27-1

分子式

C¹³H¹⁸O²

分子量

206.285

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25℃)

DMSO

≥35mg/mL

乙醇

≥35mg/mL

水

Insoluble

l  生物学信息

生物活性/药理作用

Ibuprofen is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes. This leads to decreased prostaglandin synthesis, by prostaglandin synthase, the main physiologic effect of ibuprofen. Ibuprofen also causes a decrease in the formation of thromboxane  A2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.

l  包装与存储

包 装

1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.   https://www.ncbi.nlm.nih.gov