产品名称

头孢拉定(Cephradine)

一般描述

Cephradine(头孢拉定) is a beta-lactam, first-generation cephalosporin antibiotic with bactericidal activity.

别 称

(6R,7R)-7-[[(2R)-2-amino-2-cyclohexa-1,4-dien-1-ylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Cefradine; Cephradin

纯 度

≥98%(HPLC)

CAS NO.

38821-53-3

分子式

C¹⁶H¹⁹N³O⁴S

分子量

349.405

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

浅黄色固体

溶解性(25℃)

DMSO

Insoluble

乙醇

Insoluble

水

~10mg/mL

l  生物学信息

生物活性/药理作用

Cephradine Anhydrous is the anhydrous form of cephradine, a semisynthetic, broad-spectrum, first-generation cephalosporin with antibacterial activity. Cephradine binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division. Inactivation of PBPs interferes with the cross-age  of peptidoglycan chains necessary for bacterial cell wall strength and  rigidity. This results in the weakening of the bacterial cell wall and causes cell lysis.

l  包装与存储

包 装

1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.   https://www.ncbi.nlm.nih.gov