产品名称

盐酸特比萘芬(Terbinafine Hydrochloride)

一般描述

Terbinafine Hydrochloride(盐酸特比萘芬), a synthetic allylamine derivative, is a antifungal, which blocks ergosterol biosynthesis by inhibition of squalene epoxidase.

别 称

(E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine;hydrochloride;  Terbinafine HCl

纯 度

≥99%(HPLC)

CAS NO.

78628-80-5

分子式

C²¹H²⁶ClN

分子量

327.896

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25℃)

DMSO

≥50mg/mL

乙醇

≥50mg/mL

水

Insoluble

l  生物学信息

生物活性/药理作用

Terbinafine Hydrochloride is a synthetic allylamine derivative structurally related to naftifine, antifungal Terbinafine Hydrochloride blocks ergosterol biosynthesis by inhibition of squalene epoxidase, part of the sterol synthesis pathway for the fungal cell  membrane. Highly lipophilic, it tends to accumulate in skin, nails, and fatty tissues. Terbinafine is active against dermatophytes.

l  包装与存储

包 装

1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.   https://www.ncbi.nlm.nih.gov