产品名称

恩诺沙星(Enrofloxacin)

一般描述

Enrofloxacin(恩诺沙星), a fluoroquinolone antibiotic, is a veterinary antibacterial agent, used in poultry.

别 称

1-cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-4-oxoquinoline-3-carboxylic acid; Enrofloxacine; CFPQ;  Enrofloxacino

纯 度

≥98%(HPLC)

CAS NO.

93106-60-6

分子式

C¹⁹H²²FN³O³

分子量

359.401

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

类白色或淡棕色固体

溶解性(25℃)

DMSO

~3mg/mL

乙醇

Insoluble

水

Insoluble

l  生物学信息

生物活性/药理作用

Enrofloxacin is a veterinary antibacterial  agent, used in poultry. Enrofloxacin is a synthetic chemotherapeutic agent from the class of the fluoroquinolone carboxylic acid derivatives. It has antibacterial activity against a broad spectrum of Gram-negative and Gram-positive bacteria. Its mechanism of action is not thoroughly understood,  but it is believed to act by inhibiting bacterial DNA gyrase (a type-II  topoisomerase), thereby preventing DNA supercoiling and DNA synthesis. It is a bactericidal agent. The bactericidal activity of enrofloxacin is concentration dependent, with susceptible bacteria cell death occurring within 20-30 minutes of exposure. Enrofloxacin has demonstrated a significant post-antibiotic effect for both Gram-negative and Gram-positive bacteria and  is active in both stationary and growth phases of bacterial replication.

l  包装与存储

包 装

1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.   https://www.ncbi.nlm.nih.gov