产品名称

磷酸伯氨喹(Primaquine diphosphate)

一般描述

Primaquine Phosphate(磷酸伯氨喹) is the phosphate salt form of primaquine, a synthetic, 8-aminoquinoline derivative with antimalarial properties.

别 称

8-(4-Amino-1-methylbutylamino)-6-methoxyquinoline diphosphate salt; CCRIS1946

纯 度

≥98%(HPLC)

CAS NO.

63-45-6

分子式

C¹⁵H²⁷N³O⁹P²

分子量

455.341

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

橙黄色固体

溶解性(25℃)

DMSO

≥50mg/mL

乙醇

Insoluble

水

≥50mg/mL

l  生物学信息

生物活性/药理作用

Primaquine Phosphate is the phosphate salt form of primaquine, a synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclear,  primaquine bind to and alter the properties of protozoal DNA. This agent eliminates tissue (exo-erythrocytic) malarial infection, preventing the development of the erythrocytic forms of the parasite which are responsible for relapses in  Plasmodium vivax and ovale malaria. Primaquine is active against late hepatic stages (hypnozoites, schizonts).

l  包装与存储

包 装

1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov