产品名称

盐酸特拉唑嗪(Terazosin Hydrochloride)

一般描述

Terazosin Hydrochloride(盐酸特拉唑嗪)  is the hydrochloride salt form of terazosin, a quinazoline derivative with adrenergic antagonistic property.

别 称

[4-(4-amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl]-(oxolan-2-yl)methanone;hydrochloride; Terazosin; Hytrin; Zayasel; Terazosine; Flumarc;  Fosfomic; Blavin

纯 度

≥98%(HPLC)

CAS NO.

63074-08-8

分子式

C¹⁹H²⁶ClN⁵O⁴

分子量

423.898

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25℃)

DMSO

≥50mg/mL

乙醇

Insoluble

水

~1mg/mL

l  生物学信息

生物活性/药理作用

Terazosin Hydrochloride is the hydrochloride salt form of terazosin, a quinazoline derivative with adrenergic antagonistic property. Terazosin hydrochloride selectively inhibits alpha-1 adrenergic receptors, resulting in vasodilation leading to decreased peripheral vascular resistance and a reduced venous return to the heart as well as decreased urethral resistance, which potentially improving  urine flow and symptoms related to benign prostatic hyperplasia. In addition, terazosin decreases low-density lipoproteins (LDL) and triglycerides while increasing the concentration of high-density lipoproteins (HDL).

l  包装与存储

包 装

250mg; 1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov