产品名称

盐酸万古霉素(Vancomycin HCl)

一般描述

Vancomycin Hydrochloride(盐酸万古霉素) is a branched tricyclic glycosylated peptide with bactericidal activity against most organisms and bacteriostatic effect on enterococci.

含 量

≥1050  IU/mg(anhydrous substance)

CAS NO.

1404-93-9

分子式

C⁶⁶H⁷⁵Cl²N⁹O²⁴ · HCl

分子量

1485.71

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25℃)

DMSO

Insoluble

乙醇

Insoluble

水

≥50mg/mL

l  生物学信息

生物活性/药理作用

Vancomycin Hydrochloride is the hydrochloride salt of vancomycin, a branched tricyclic glycosylated peptide with bactericidal activity against most organisms and bacteriostatic effect on enterococci. At a site different from that of penicillins and cephalosporins, vancomycin binds tightly to the D-alanyl-D-alanine portion of cell wall precursors, thereby interfering with bacterial cell wall synthesis. This leads to activation of bacterial autolysins that destroy the cell wall by lysis. Vancomycin may also alter the permeability of bacterial cytoplasmic membranes and may selectively inhibit RNA synthesis.

l  包装与存储

包 装

250mg; 1g

存储温度

-20℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov