产品名称

哈西奈德(Halcinonide)

一般描述

Halcinonide(哈西奈德) is a topical, synthetic glucocorticoid with anti-inflammatory and anti-allergic properties.

别 称

(11β, 16α)-21-Chloro-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]pregn-4-ene-3,20-dione

纯 度

≥98%(HPLC)

CAS NO.

3093-35-4

分子式

C²⁴H³²ClFO⁵

分子量

454.96

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25℃)

DMSO

≥50mg/mL

乙醇

~4mg/mL

水

Insoluble

l  生物学信息

生物活性/药理作用

Halcinonide is a topical, synthetic glucocorticoid with anti-inflammatory and anti-allergic properties. Halcinonide exerts its effect by interacting with specific intracellular receptors, and the ligand-receptor complex subsequently modulates gene s via the typical glucocorticoid signalling pathway. This results in the synthesis of certain anti-inflammatory proteins as well as in synthesis inhibition of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are accomplished.

l  包装与存储

包 装

250mg;1g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov