Flavopiridol Hydrochloride
商品编号：
TL0480
备注：
库存充足，如需更大包装，请联系销售人员，大包装有极大的折扣优惠！
详细介绍
l 基本信息 |
产品名称 | 夫拉平度盐酸盐(Flavopiridol Hydrochloride) |
一般描述 | Flavopiridol Hydrochloride(夫拉平度盐酸盐) is a synthetic flavonoid based on an extract from an Indian plant for the potential treatment of cancer. |
别 称 | NSC 649890 HCl; Alvocidib hydrochloride; |
纯 度 | ≥98.0%(HPLC) | CAS NO. | 131740-09-5 |
分子式 | C21H21Cl2NO5 | 分子量 | 438.30 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 固体 |
溶解性(25℃) | DMSO | ≥50mg/mL |
乙醇 | Very
slightly soluble |
水 | Insoluble |
l 生物学信息 |
生物活性/药理作用 | Alvocidib is the free base form of a synthetic N-methylpiperidinyl chlorophenyl flavone compound. As an inhibitor of cyclin-dependent kinase, alvocidib induces cell cycle arrest by preventing phosphorylation of cyclin-dependent kinases (CDKs) and by down-regulating cyclin D1 and D3 , resulting in G1 cell cycle arrest and apoptosis. This agent is also a competitive inhibitor of adenosine triphosphate activity. |
l 包装与存储 |
包 装 | 5mg; 25mg; 100mg |
存储温度 | -20℃ |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
