Emtricitabine
商品编号：
TL0499
备注：
库存充足，如需更大包装，请联系销售人员，大包装有极大的折扣优惠！
详细介绍
l 基本信息 |
产品名称 | 恩曲他滨(Emtricitabine) |
一般描述 | Emtricitabine(恩曲他滨) is a nucleoside analogue and reverse tranase inhibitor. |
别 称 | 4-amino-5-fluoro-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one; |
纯 度 | ≥99.0%(HPLC) | CAS NO. | 143491-57-0 |
分子式 | C8H10FN3O3S | 分子量 | 247.25 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 白色或类白色固体 |
溶解性(25℃) | DMSO | ≥45mg/mL |
乙醇 | ≥5mg/mL |
水 | ≥45mg/mL |
l 生物学信息 |
生物活性/药理作用 | Emtricitabine is a synthetic fluoro derivative of thiacytidine with potent antiviral activity. Emtricitabine is phosphorylated to form emtricitabine 5'-triphosphate within the cell. This metabolite inhibits the activity of human immunodeficiency virus (HIV) reverse tranase both by competing with the natural substrate deoxycytidine 5'-triphosphate and by incorporation into viral DNA causing a termination of DNA chain elongation (due to the lack of the essential 3'-OH
group). |
l 包装与存储 |
包 装 | 250mg; 1g; 5g |
存储温度 | -20℃ |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
