产品名称

头孢地尼(Cefdinir)

一般描述

Cefdinir(头孢地尼) is a semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity.

别 称

syn-7-[2-(2-amino-4-thiazolyl)-2-hydroxyiminoacetamido]-3-vinyl-3-cephem-4-carboxylic acid;FK 482

纯 度

≥98.0%(HPLC)

CAS NO.

91832-40-5

分子式

C¹⁴H¹³N⁵O⁵S²

分子量

395.408

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

浅黄色固体

溶解性(25℃)

DMSO

≥50mg/mL

乙醇

Very slightly soluble

水

Insoluble

l  生物学信息

生物活性/药理作用

Cefdinir is a semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefdinir's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the   transpeptidase enzymes, thereby preventing cross-ing of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefdinir inhibits bacterial septum and cell wall synthesis formation.

l  包装与存储

包 装

250mg; 1g; 5g

存储温度

-20℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov