产品名称

阿马林((±)-Ajmaline)

一般描述

(±)-Ajmaline(阿马林) is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials.

别 称

Ajmalin; 阿义吗啉; Cartagine; Ajmalin; Rytmalin;

纯 度

≥95.0%(HPLC)

CAS NO.

4360-12-7

分子式

C²⁰H²⁶N²O²

分子量

326.439

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25℃)

DMSO

≥15mg/mL

乙醇

Sparingly soluble

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Ajmaline is a class 1A antiarrhythmic agent. By interfering with the sodium channels, this drug allows for improvement in abnormal rhythms of the heart.

The class I antiarrhythmic agents interfere with the sodium channel. A class IA agent lengthens the action potential (right shift) which brings about improvement in abnormal heart rhythms. This drug in particular has a high affinity for the Nav 1.5 sodium channel.

l  包装与存储

包 装

10mg; 25mg

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov