产品名称

盐酸异丙嗪(Promethazine hydrochloride)

一般描述

Promethazine hydrochloride is a phenothiazine derivative with histamine H1-blocking, antimuscarinic, and sedative properties.

别 称

10-[2-(Dimethylamino)propyl]phenothiazine hydrochloride;Promethazine Hcl

纯 度

≥99.0%(HPLC)

CAS NO.

58-33-3

分子式

C¹⁷H²¹ClN²S

分子量

320.88

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25℃)

DMSO

≥50mg/mL

乙醇

≥30mg/mL

水

≥50mg/mL

l  生物学信息

生物活性/药理作用

Promethazine Hydrochloride is the hydrochloride salt form of promethazine, a phenothiazine derivative with antihistaminic, sedative and antiemetic properties. Promethazine hydrochloride selectively blocks peripheral H1 receptors thereby diminishing the effects of histamine on effector cells. Promethazine hydrochloride also blocks the central histaminergic receptors, thereby depressing the reticular system causing sedative and hypnotic effects. In addition, promethazine hydrochloride also has centrally acting anticholinergic properties and probably mediates nausea and vomiting by acting on the medullary chemoreceptive trigger zone.

l  包装与存储

包 装

1g; 5g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov