产品名称

奥卡西平(Oxcarbazepine)

一般描述

Oxcarbazepine is a dibenzazepine carboxamide derivative with an anticonvulsant property.

别 称

10,11-Dihydro-10-oxo-5h-dibenz[b,f]azepine-5-carboxamide;GP47680

纯 度

≥99.0%(HPLC)

CAS NO.

28721-07-5

分子式

C¹⁵H¹²N²O²

分子量

252.27

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25℃)

DMSO

≥5mg/mL

乙醇

Insoluble

水

Insoluble

l  生物学信息

生物活性/药理作用

Oxcarbazepine is a dibenzazepine carboxamide derivative with an anticonvulsant property. As a prodrug, oxcarbazepine is converted to its active metabolite, 10-monohydroxy. Although the mechanism of action has not been fully elucidated, electrophysiological studies indicate this agent blocks voltage-gated sodium channels, thereby stabilizing hyper-excited neural membranes, inhibiting repetitive neuronal firing, and decreasing the propagation of synaptic impulses.

l  包装与存储

包 装

1g; 5g

存储温度

0-5℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov