Dabigatran Etexilate Mesylate
商品编号:
TL0632
备注:
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详细介绍
l 基本信息 |
产品名称 | 甲磺酸达比加群酯(Dabigatran Etexilate Mesylate) |
一般描述 | Dabigatran Etexilate Mesylate is the prodrug of dabigatran. |
别 称 | ethyl 3-[[2-[[4-[(Z)-N'-hexoxycarbonylcarbamimidoyl]anilino]methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate;methanesulfonic acid |
纯 度 | ≥98.0%(HPLC) | CAS NO. | 872728-81-9 |
分子式 | C35H45N7O8S | 分子量 | 723.846 |
适用范围 | 生物试剂,适用于细胞培养等 |
l 理化信息 |
外 观 | 浅黄色或黄色固体 |
l 生物学信息 |
生物活性/药理作用 | Dabigatran Etexilate Mesylate is an orally available mesylate salt form of the etexilate prodrug of dabigatran, a benzimidazole and direct thrombin inhibitor with anticoagulant activity. Upon administration, dabigatran etexilate is hydrolyzed by esterases and is converted into dabigatran. Dabigatran reversibly binds to and inhibits the activity of thrombin, a serine protease that converts fibrinogen into fibrin. This disrupts the coagulation cascade and inhibits the formation of blood clots. |
l 包装与存储 |
包 装 | 50mg; 250mg; 1g |
存储温度 | 0-5℃ |
l 注意事项及免责声明 |
本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |