产品名称

头孢丙烯(Cefprozil)

一般描述

Cefprozil s a semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity.

别 称

(6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(E)-prop-1-enyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid;Cefprozilum; Cefprozil anhydrous

纯 度(HPLC)

≥98%(Cefprozil (Z)-Isomer + Cefprozil (E)-Isomer);

(E)-isomer ratio=(E/(E+Z)), the ratio is between 0.06 and 0.11;

CAS NO.

92665-29-7

分子式

C¹⁸H¹⁹N³O⁵S

分子量

389.43

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

类白色或浅黄色固体

溶解性(25℃)

DMSO

≥25mg/mL

乙醇

≥10mg/mL

水

Slightly soluble

l  生物学信息

生物活性/药理作用

Cefprozil is a semi-synthetic cephalosporin and a beta-lactam antibiotic with bactericidal activity. Cefprozil's effect is dependent on its binding to penicillin-binding proteins (PBPs) located in the bacterial cytoplasmic membrane. Binding results in the inhibition of the transpeptidase enzymes, thereby preventing cross-ing of the pentaglycine bridge with the fourth residue of the pentapeptide and interrupting consequent synthesis of peptidoglycan chains. As a result, cefprozil inhibits bacterial septum and cell wall synthesis formation.

l  包装与存储

包 装

25mg; 100mg; 250mg

存储温度

-20℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov