产品名称

头孢呋辛钠(Cefuroxime Sodium)

一般描述

Cefuroxime Sodium is a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal activity.

别 称

sodium;(6R,7R)-3-(carbamoyloxymethyl)-7-[[(2Z)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Kefurox

纯 度

≥98.0%(HPLC)

CAS NO.

56238-63-2

分子式

C¹⁶H¹⁵N⁴NaO⁸S

分子量

446.37

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

浅黄色或黄色固体

溶解性(25℃)

DMSO

≥50mg/mL

乙醇

Insoluble

水

≥50mg/mL

l  生物学信息

生物活性/药理作用

Cefuroxime Sodium is the sodium salt form of cefuroxime and a semi-synthetic, broad-spectrum, beta-lactamase resistant, second-generation cephalosporin antibiotic with bactericidal activity. Cefuroxime sodium inhibits bacterial cell wall synthesis by inactivating   penicillin binding proteins (PBPs) thereby interfering with the final transpeptidation step required for cross-ing of peptidoglycan units which are a component of the cell wall. Lack of cross-ing results in a reduction of cell wall stability and leads to cell lysis.

l  包装与存储

包 装

250mg; 1g

存储温度

-20℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov