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Divalproex Sodium

商品编号: TL0700
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详细介绍

l  基本信息

产品名称

丙戊酸半钠(Divalproex   Sodium)

一般描述

Divalproex   Sodium is a stable coordination compound comprised of sodium valproate and   valproic acid with anticonvulsant and antiepileptic activities.

别 称

Valproate   semisodium

纯 度

≥99.0%(HPLC)

CAS   NO.

76584-70-8

分子式

C16H31NaO4

分子量

310.40

适用范围

生物试剂,适用于细胞培养等

l  理化信息

外 观

白色固体

溶解性(25℃)

DMSO

≥50mg/mL

乙醇

≥50mg/mL

≥50mg/mL

l  生物学信息

生物活性/药理作用

Divalproex   Sodium is a stable coordination compound comprised of sodium valproate and   valproic acid with anticonvulsant and antiepileptic activities. Divalproex   dissociates to the valproate ion in the gastrointestinal tract. This agent   binds to and inhibits gamma-aminobutyric acid (GABA) transaminase and its   anticonvulsant activity may be exerted by increasing brain concentration of   GABA and by inhibiting enzymes that catabolize GABA or block the reuptake of   GABA into glia and nerve endings. Divalproex may also work by suppressing   repetitive neuronal firing through inhibition of voltage-sensitive sodium   channels.

应 用

1.     Anticonvulsants

2.     Antimanic   Agents

3.     Enzyme   Inhibitors

4.     GABA   Agents

l  包装与存储

包 装

250mg; 1g

存储温度

0-5

l  注意事项及免责声明

本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov