Granisetron hydrochloride
商品编号：
TL0720
备注：
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详细介绍
l 基本信息 |
产品名称 | 盐酸格拉司琼(Granisetron hydrochloride) |
一般描述 | Granisetron hydrochloride is a serotonin receptor (5HT-3 selective) antagonist that has been used as an antiemetic for cancer chemotherapy patients. |
别 称 | 1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide hydrochloride |
纯 度 | ≥99.0%(HPLC) | CAS NO. | 107007-99-8 |
分子式 | C18H24N4O · HCl | 分子量 | 348.87 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 白色或类白色固体 |
溶解性(25℃) | DMSO | Very slightly soluble |
乙醇 | Very slightly soluble |
水 | ≥50mg/mL |
l 生物学信息 |
生物活性/药理作用 | Granisetron Hydrochloride is the hydrochloride salt of an indazole derivative with antiemetic properties. As a selective serotonin receptor antagonist, granisetron competitively blocks the action of serotonin at 5-hydroxytryptamine3 (5-HT3) receptors, resulting in the suppression of chemotherapy- and radiotherapy-induced nausea and vomiting. |
l 包装与存储 |
包 装 | 50mg; 250mg; 1g |
存储温度 | -20℃ |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
