产品名称

桂利嗪(Cinnarizine)

一般描述

Cinnarizine(桂利嗪) is a piperazine derivative having histamine H1-receptor and calcium-channel blocking activity with vasodilating and antiemetic properties but it induces   Parkinsonian disorders.

别 称

1-benzhydryl-4-[(E)-3-phenylprop-2-enyl]piperazine; Stugeron

纯 度

≥99.0%(HPLC)

CAS NO.

298-57-7

分子式

C²⁶H²⁸N²

分子量

368.524

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色或类白色固体

溶解性(25℃)

DMSO

≥50mg/mL

乙醇

Very slightly soluble

水

Insolube

l  生物学信息

生物活性/药理作用

Cinnarizine is a piperazine derivative having histamine H1-receptor and calcium-channel blocking activity with vasodilating and antiemetic properties but it induces PARKINSONIAN DISORDERS.

Cinnarizine is a N-alkylpiperazine. It has a role as an antiemetic, a histamine antagonist, a calcium channel blocker, a muscarinic antagonist, an anti-allergic agent and a H1-receptor antagonist.

l  存储

存储温度

-20℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov