产品名称

炔诺酮(Norethindrone)

一般描述

Norethindrone(炔诺酮) is a synthetic progestational substance with some anabolic, estrogenic, and androgenic properties.

别 称

(8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one; Norethisterone; Norethisteron;

纯 度

≥99.0%(HPLC)

CAS NO.

68-22-4

分子式

C²⁰H²⁶O²

分子量

298.426

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色固体

溶解性(25℃)

DMSO

≥50mg/mL

乙醇

Slightly soluble

水

Insolube

l  生物学信息

生物活性/药理作用

Norethindrone is a synthetic progestational substance with some anabolic, estrogenic, and androgenic properties. Norethindrone binds to the progesterone intracellular receptors in the reproductive system and the resultant activated complex interacts with specific DNA sites. This leads to an alteration in protein synthesis and results in an inhibition of LH release. Consequently, it inhibits ovulation and changes the normal cycle of cervical mucus and endometrium.

l  存储

存储温度

-20℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov