产品名称

DL-Dihydroorotic acid

一般描述

DL-Dihydroorotic acid is a substrate of the enzyme orotate reductase, which is part of the pyrimidine metabolism pathway.

别 称

4, 5-Dihydroorotic acid

纯 度

≥98.0%(TLC)

CAS NO.

6202-10-4

分子式

C⁵H⁶N²O⁴

分子量

158.11

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色固体

溶解性(25℃)

DMSO

≥10mg/mL

水

Slightly soluble

l  生物学信息

生物活性/药理作用

4, 5-Dihydroorotic acid is a substrate of the enzyme orotate reductase [EC 1. 3. 1. 14], which is part of the pyrimidine metabolism pathway. (KEGG) Dihydroorotate is oxidized by Dihydroorotate dehydrogenases (DHODs) to orotate. These dehydrogenases use their FMN (flavin mononucleotide) prosthetic group to abstract a hydride equivalent from C6 to deprotonate C5.

l  存储

存储温度

-20℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.   https://www.ncbi.nlm.nih.gov