Sapitinib(AZD8931)
商品编号：
TL0934
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详细介绍
l 基本信息 |
产品名称 | Sapitinib(沙普替尼) |
一般描述 | Sapitinib is an erbB receptor tyrosine kinase inhibitor with potential antineoplastic activity. |
别 称 | AZD-8931 |
纯 度 | ≥98%(HPLC) | CAS NO. | 848942-61-0 |
分子式 | C23H25ClFN5O3 | 分子量 | 473.93 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 白色或类白色固体 |
溶解性(25°C) | DMSO | ≥50mg/mL |
乙醇 | Insoluble |
水 | Insoluble |
l 生物学信息 |
生物活性/药理作用 | Sapitinib is an erbB receptor tyrosine kinase inhibitor with potential antineoplastic activity. erbB kinase inhibitor AZD8931 binds to and inhibits erbB tyrosine receptor kinases, which may result in the inhibition of cellular proliferation and angiogenesis in tumors expressing erbB. The erbB protein family, also called the epidermal growth factor receptor (EGFR) family, plays major roles in tumor cell proliferation and tumor vascularization. |
l 存储 |
存储温度 | -20℃ |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
