产品名称

Danazol(达那唑)

一般描述

Danazol is a synthetic androgen derived from ethinyl testosterone.

别 称

WIN-17757; 2,3-Isoxazolethisterone

纯 度

≥98.5%(HPLC)

CAS NO.

17230-88-5

分子式

C²²H²⁷NO²

分子量

337.46

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至米色固体

溶解性(25°C)

DMSO

≥50mg/mL

乙醇

≥25mg/mL

水

Very slightly soluble

l  生物学信息

生物活性/药理作用

Danazol is a derivative of the synthetic steroid ethisterone, a modified testosterone. It was approved by the U.S. Food and Drug Administration (FDA) as the first drug to specifically treat endometriosis, but its role as a treatment for endometriosis has been largely replaced by the gonadotropin-releasing hormone (GnRH) agonists. Danazol has antigonadotropic and anti estrogenic activities. Danazol acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties.

l  存储

存储温度

0-5°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov