产品名称

Prochlorperazine dimaleate salt

一般描述

Prochlorperazine dimaleate is a dopamine (D2) receptor antagonist.

别 称

Prochlorperazin, Compazine, Capazine, Stemetil

纯 度

≥99%(HPLC)

CAS NO.

84-02-6

分子式

C²⁸H³²ClN³O⁸S

分子量

606.09

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

淡黄或黄绿色固体

溶解性(25°C)

DMSO

≥45mg/ml

乙醇

Slightly soluble

水

Insoluble

l  生物学信息

生物活性/药理作用

Prochlorperazine Maleate is the maleate salt form of prochlorperazine, a synthetic, piperazinephenothiazine derivative with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine binds to and blocks the postsynaptic dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy induced emesis. Prochlorperazine maleate also blocks anticholinergic and alpha-adrenergic receptors. Its antagonistic actions on the alpha-1 adrenergic receptors results in sedation, muscle relaxation, and hypotension.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov