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详细介绍
l 基本信息 |
产品名称 | Mirtazapine(米氮平) |
一般描述 | Mirtazapine is an adrenergic and seroton receptor antagonist, used to treat depression. |
别 称 | Org3770; 5-methyl-2,5,19-triazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(15),8,10,12,16,18-hexaene |
纯 度 | ≥98.0%(HPLC) | CAS NO. | 85650-52-8 |
分子式 | C17H19N3 | 分子量 | 265.36 |
适用范围 | 生物试剂,适用于细胞培养等 |
l 理化信息 |
外 观 | 白色至类白色粉末 |
溶解性(25°C) | DMSO | ≥45mg/mL |
乙醇 | ≥45mg/mL |
水 | Insoluble |
l 生物学信息 |
生物活性/药理作用 | Mirtazapine is a synthetic tetracyclic derivative of the piperazino-azepines with antidepressant activity. Although its mechanism of action is unknown, mirtazapine enhances central adrenergic and serotonergic transmission, possibly by acting as an antagonist at central presynaptic alpha 2 adrenergic inhibitory autoreceptors and heteroreceptors. This agent is a potent antagonist of 5-hydroxytryptamine type 2 (5-HT2), 5-HT3, and histamine 1 (H1) receptors, and a moderate antagonist of peripheral alpha 1 adrenergic and muscarinic receptors. |
l 存储 |
存储温度 | -20°C |
l 注意事项及免责声明 |
本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |