产品名称

Thioridazine hydrochloride(盐酸硫利达嗪)

一般描述

Thioridazine hydrochloride is a potent antianxiety and antipsychotic agent.

别 称

Aldazine, Mellaril; 10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfanylphenothiazine; hydrochloride

纯 度

≥98.0%(HPLC)

CAS NO.

130-61-0

分子式

C²¹H²⁷ClN²S²

分子量

407.04

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色固体

溶解性(25°C)

DMSO

≥50mg/ml

l  生物学信息

生物活性/药理作用

Thioridazine Hydrochloride is the hydrochloride salt form of thioridazine, a piperidine phenothiazine derivative and a dopamine antagonist with antipsychotic property. Thioridazine hydrochloride binds to mesolimbic postsynaptic dopaminereceptor D2, thereby decreasing dopamine activity leading to decreased psychotic effects, such as hallucinations and delusions. In addition, this agent binds to serotonin 5-HT2 receptors, resulting in decreased serotonin activity.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov