产品名称

Formoterol Fumarate Dihydrate(富马酸福莫特罗二水合物)

一般描述

Formoterol Fumarate Dihydrate is a potent, selective and long-acting β2-adrenoceptor agonist used in the management of asthma and chronic obstructive pulmonary disease(COPD).

别 称

Formoterol fumarate hydrate

纯 度

≥99.0%(HPLC)

CAS NO.

183814-30-4

分子式

C¹⁹H²⁴N²O⁴ · 0.5C⁴H⁴O⁴ · H²O

分子量

420.46

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色至类白色固体

溶解性(25°C)

DMSO

≥25mg/mL

乙醇

Insoluble

水

Insoluble

l  生物学信息

生物活性/药理作用

Formoterol Fumarate is the fumarate salt form of formoterol, a long-acting and selective sympathomimetic beta-receptor agonist with bronchodilator activity. Formoterol fumarate binds beta 2 adrenergic receptors in bronchial smooth muscle and stimulates intracellular adenyl cyclase, thereby increasing the production of cyclic adenosine monophosphate (cAMP). Increased cAMP levels cause relaxation of bronchial smooth muscle, improve mucociliary clearance and reduce mediator substance release in inflammatory cells, especially from mast cells.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov