产品名称

盐酸苯乙福明(Phenformin HCl)

一般描述

Phenformin Hydrochloride(盐酸苯乙福明) is the hydrochloride salt form of phenformin, an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity.

别 称

1-(diaminomethylidene)-2-(2-phenylethyl)guanidine;hydrochloride; Phenethylbiguanide hydrochloride

纯 度

≥98.0%(HPLC)

CAS NO.

834-28-6

分子式

C¹⁰H¹⁶ClN⁵

分子量

241.72

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25℃)

DMSO

≥45mg/mL

乙醇

≥10mg/mL

水

≥45mg/mL

l  生物学信息

生物活性/药理作用

Phenformin Hydrochloride is the hydrochloride salt form of phenformin, an agent belonging to the biguanide class of antidiabetics with antihyperglycemic activity. Phenformin is not used clinically due to the high risk of lactic acidosis that is associated with its use.

Phenformin HCl activates AMPK, increasing activity and phosphorylation.

l  存储

存储温度

-20℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov