产品名称

烟酰胺(Nicotinamide (Vitamin B3))

一般描述

Nicotinamide, a water-soluble vitamin, is an active component of coenzymes NAD and NADP, and also act as an inhibitor of sirtuins.

别 称

pyridine-3-carboxamide; Niacinamide, Vitamin PP, Nicotinic acid amide

纯 度

≥98.0%(HPLC)

CAS NO.

98-92-0

分子式

C⁶H⁶N²O

分子量

122.12

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25℃)

DMSO

≥20mg/mL

乙醇

≥20mg/mL

水

≥20mg/mL

l  生物学信息

生物活性/药理作用

Niacinamide is the active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy.

l  存储

存储温度

-20℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov