产品名称

(-)-表没食子儿茶素没食子酸酯((-)-Epigallocatechin Gallate)

一般描述

(-)-Epigallocatechin Gallate is a phenolic antioxidant found in a number of plants such as green and black tea.

别 称

[(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-3,4-dihydro-2H-chromen-3-yl]  3,4,5-trihydroxybenzoate; EGCG

纯 度

≥98.0%(HPLC)

CAS NO.

989-51-5

分子式

C²²H¹⁸O¹¹

分子量

458.37

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25℃)

DMSO

≥50mg/mL(warmed)

乙醇

≥50mg/mL(warmed)

水

≥20mg/mL(warmed)

l  生物学信息

生物活性/药理作用

(-)-Epigallocatechin Gallate is a phenolic antioxidant found in a number of plants such as green and black tea. It inhibits cellular oxidation and prevents free radical damage to cells. It is under study as a potential cancer chemopreventive agent.

(-)-Epigallocatechin Gallate(EGCG) is the main catechin extraction of green tea that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF receptors and HER-2 receptors. ECGG inhibits fatty acid synthase and glutamate dehydrogenase activity.

l  存储

存储温度

-20℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov