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Verapamil HCl

商品编号: TS0417
图示 货号 库存 价格(¥) 数量

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详细介绍

l  基本信息

产品名称

盐酸维拉帕米(Verapamil HCl)

一般描述

Verapamil hydrochloride is a calcium channel blocker that is a class IV anti-arrhythmia agent.

别 称

2-(3,4-dimethoxyphenyl)-5-[2-(3,4-dimethoxyphenyl)ethyl-methylamino]-2-propan-2-ylpentanenitrile;hydrochloride

纯 度

≥97.0%(HPLC)

CAS NO.

152-11-4

分子式

C27H38N2O4·HCl

分子量

491.06

适用范围

生物试剂,适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25)

DMSO

≥50mg/mL

乙醇

≥10mg/mL

≥50mg/mL

l  生物学信息

生物活性/药理作用

Verapamil Hydrochloride is the hydrochloride form of Verapamil, which is a phenylalkylamine calcium channel blocking agent. Verapamil inhibits the transmembrane influx of extracellular calcium ions into myocardial and vascular smooth muscle cells, causing dilatation of the main coronary and systemic arteries and decreasing myocardial contractility. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in some multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents.

l  存储

存储温度

-20

l  注意事项及免责声明

本产品仅用于实验研究,不得作为药物使用,不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov