产品名称

乙琥胺(Ethosuximide)

一般描述

Ethosuximide is a succinimide with anticonvulsant activity.

别 称

3-ethyl-3-methylpyrrolidine-2,5-dione

纯 度

≥98.0%(HPLC)

CAS NO.

77-67-8

分子式

C⁷H¹¹NO²

分子量

141.17

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

固体

溶解性(25℃)

DMSO

≥25mg/mL

乙醇

≥25mg/mL

水

≥25mg/mL

l  生物学信息

生物活性/药理作用

Ethosuximide is a succinimide with anticonvulsant activity. The exact mechanism of action is not entirely understood, but most likely ethosuximide exerts its effects by partial antagonism of T-type calcium channels of the thalamic neurons. This leads to a decrease in burst firing of thalamocortical neurons, which stabilizes the nerve activity in the brain and prevents seizures.

l  存储

存储温度

-20℃

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov