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详细介绍
l 基本信息 |
产品名称 | 阿比特龙(Abiraterone) |
一般描述 | Abiraterone is a steroidal compound with antiandrogen activity. |
别 称 | (3S,8R,9S,10R,13S,14S)-10,13-dimethyl-17-pyridin-3-yl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-3-ol; CB-7598 |
纯 度 | ≥98.0%(HPLC) | CAS NO. | 154229-19-3 |
分子式 | C24H31NO | 分子量 | 349.51 |
适用范围 | 生物试剂，适用于细胞培养等 |
l 理化信息 |
外 观 | 固体 |
溶解性(25℃) | DMSO | Very slightly soluble |
乙醇 | Very slightly soluble |
DMF | ~4mg/mL(warmed) |
l 生物学信息 |
生物活性/药理作用 | Abiraterone is a steroidal compound with antiandrogen activity. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex; CYP17A1), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis. Administration of this agent may suppress testosterone production by both the testes and the adrenals to castrate-range levels. |
l 存储 |
存储温度 | -20℃ |
l 注意事项及免责声明 |
本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。 |
l 参考文献 |
1. http://www.drugbank.ca 2. https://ncit.nci.nih.gov 3. https://www.ncbi.nlm.nih.gov |
