产品名称

Eptifibatide Acetate(醋酸依替巴肽)

一般描述

Eptifibatide Acetate is a cyclic heptapeptide constructed from 6 amino acids and a mercaptopropionyl residue.  A disulfide bridge forms between mercaptopropionyl and cysteine. Eptifibatide prevents platelet aggregation. One study shows the inhibition of platelet glycoprotein IIb/IIIa in acute coronary syndromes.

别 称

Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2

纯 度

≥98.0%(HPLC)

CAS NO.

148031-34-9

分子式

C³⁵H⁴⁹N¹¹O⁹S²

分子量

831.965

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

白色固体

溶解性(25°C)

水

Insoluble

l  生物学信息

生物活性/药理作用

Eptifibatide is a cyclical heptapeptide with anticoagulant activity. Eptifibatide selectively and reversibly binds to and blocks the platelet glycoprotein IIb/IIIa receptor. This prevents the binding of fibrinogen, von Willebrand factor, and other adhesive ligands and leads to an inhibition of platelet aggregation and prevents thrombus development.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov