产品名称

Gonadorelin Acetate(醋酸戈那瑞林)

一般描述

Gonadorelin Acetate is another name for gonadotropin-releasing hormone (GnRH). It is a synthetic decapeptide prepared using solid phase peptide synthesis.

别 称

Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2

纯 度

≥98% (HPLC)

CAS NO.

71447-49-9

分子式

C⁵⁵H⁷⁵N¹⁷O¹³_·xC²H⁴O²

分子量

1182.311(free base basis)

适用范围

生物试剂，适用于细胞培养等

l  理化信息

外 观

固体

l  生物学信息

生物活性/药理作用

Recombinant Gonadorelin is a synthetic luteinizing hormone releasing hormone (LHRH) identical to or similar to the endogenous hormone. Synthesized in and secreted by the hypothalamus, gonadorelin binds to transmembrane LHRH receptors on pituitary gonadotrophic cells, thereby stimulating synthesis and secretion of gonadotropins. Continuous administration of gonadorelin desensitizes the gonadotrophic cells, a negative feedback effect. This agent can be used in treatment of hypothalamic amenorrhea and evaluation of hypothalamic/pituitary function.

l  存储

存储温度

-20°C

l  注意事项及免责声明

本产品仅用于实验研究，不得作为药物使用，不得用于家用或其它用途。

l  参考文献

1.    http://www.drugbank.ca

2.    https://ncit.nci.nih.gov

3.    https://www.ncbi.nlm.nih.gov